Maternale

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Pasgeborenen en jonge, nog niet of onvoldoende gevaccineerde zuigelingen vormen de belangrijkste risicogroep voor het krijgen van een ernstige kinkhoestinfectie. Just as the placenta's physiology is designed to transfer resources from the maternal body to the offspring in the womb 3, 5, the physiology of fetal cells in maternal tissues may enhance resource transfer to the offspring after parturition through, for example enhancing lactation or heat transfer.

Maternal pertussis vaccination is effective in preventing pertussis infection in infants aged <8 weeks and may be considered in other countries experiencing high levels of pertussis notifications. Further, in RA patients, symptoms tend to only show improvement during pregnancy, but exacerbation of symptoms postpartum 100.Participants 20 074 pregnant women with a median age of 30 who received the pertussis vaccine and a matched historical unvaccinated control group. Together these findings suggest that fetal microchimeric cells may play a role in breast physiology and milk supply, but the effects on maternal health are not yet clear. Here we review these contradictory findings and describe how the cooperation and conflict framework can help elucidate both the proximate and evolutionary function of fetal cells in maternal tissues (Table 1). n. als “het overlijden van een vrouw door rechtstreekse of onrechtstreekse obstetrische oorzaken meer dan 42 dagen, maar minder dan een jaar, na beëindiging van de zwangerschap. pertussis) antigens, were developed in the hope that they would be as effective, but less reactogenic than the whole-cell vaccines.

g. gestational diabetes and preeclampsia) that have been attributed to escalating maternal‐fetal conflict during pregnancy 3, 5. By joining TV Guide, you agree to our Terms of Use and acknowledge the data practices in our Privacy Policy. The primary endpoint were GCMs and expected infant seropositivity rates, defined by birth anti-PT >30 EU/ml to confer seropositivity until 3 months of age. During pregnancy, fetal cells may operate as an extension of the placenta, helping to coordinate manipulation of maternal resource transfer to the offspring across maternal tissues. This predicts that the presence of fetal cells in the breast should be associated with higher levels of milk production or enhanced quality of mother's milk and could be associated with negative health outcomes for the mother in some cases 52.

We use cooperation and conflict theory to generate testable predictions about domains in which fetal microchimerism may enhance maternal health and those in which it may be detrimental.