The recommended dose depends on the type of diarrhoea you have and your age. Adults (over 18), with short-term diarrhoea or IBS If you are constipated , or your stomach appears swollen (especially in children with severe dehydration).

The tablets contain loperamide hydrochloride, a substance that helps reduce diarrhoea by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Before taking this medicine IMODIUM® can have side effects, like all medicines, although these don’t affect everyone and most are usually mild. Get medical help at once Now read this whole leaflet carefully before you use this medicine. Keep the leaflet: you might need it again. 1 What the medicine is for Absorption: Most ingested loperamide is absorbed from the gut, but as a result of significant first pass metabolism, systemic bioavailability is only approximately 0.3%. Upon cessation, cases of drug withdrawal syndrome have been observed in individuals abusing, misusing, or intentionally overdosing with excessively large doses of loperamide.This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium-free'. If your doctor has prescribed loperamide for you or your child, follow their instructions about how and when to take it. How to take it

In individuals who have ingested overdoses of loperamide, cardiac events such as QT interval and QRS complex prolongation, torsades de pointes, other serious ventricular arrhythmias, cardiac arrest and syncope have been observed (see section 4.4). Fatal cases have also been reported. Overdose can unmask existing Brugada syndrome.Since persistent diarrhoea can be an indicator of potentially more serious conditions, Imodium Instant Melts should not be used for prolonged periods until the underlying cause of the diarrhoea has been investigated. You can also report side effects directly via the Yellow Card Scheme at: or search for MHRA Yellow Card in the Google Play or Apple App Store.

Although no pharmacokinetic data are available in patients with hepatic impairment, Imodium Instant Melts should be used with caution in such patients because of reduced first pass metabolism, as it may result in a relative overdose leading to CNS toxicity. Although no pharmacokinetic data are available in patients with hepatic impairment, Imodium Instant Melts should be used with caution in such patients because of reduced first pass metabolism. (see 4.4 Special warnings and special precautions for use). headaches – make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Talk to your doctor if the headaches last longer than a week or are severe.Mint flavour contains traces of sulphites. This may rarely cause severe hypersensitivity reactions and bronchospasm. Age 12 to 17 years with IBS or long-lasting diarrhoea – follow the instructions from their doctor. This is given on prescription only. farting (wind) – avoid foods that cause wind like lentils, beans and onions. It might also help to eat smaller and more frequent meals, eat and drink slowly, and exercise regularly. There are products you can buy from a pharmacy to help with wind. Loperamide can be bought mixed with simeticone, a medicine for wind. In case of overdose (including relative overdose due to hepatic dysfunction), CNS depression (stupor, coordination abnormality, somnolence, miosis, muscular hypertonia and respiratory depression), constipation, urinary retention and ileus may occur. Children, and patients with hepatic dysfunction, may be more sensitive to CNS effects. Loss of consciousness or reduced level of consciousness (passing out, feeling faint or less alert), uncoordinated movements.