discontinued - use lotoprednol post-op in patients who have previously developed a disproportionate increase in intra ocular pressure when treated with traditional corticosteroids In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. microgram/mL preservative free (PF) eye drops- restricted use for patients requiring a PF product; available as both unit-dose (minims) andmulti-dose bottles

SYSTANE COMPLETE also takes the guesswork out of choosing an artificial tear because it’s designed to provide symptom relief for every major type of dry eye—aqueous-deficient, evaporative/MGD, and mixed dry eye—the drop has everything patients need to increase tear volume and restore the lipid layer. Propylene Glycol 0.6%, Hydroxypropyl Guar, Mineral Oil, Dimyristoyl Phosphatidylglycerol, Polyoxyl 40 Stearate, Sorbitan Tristearate, Boric Acid, Sorbitol, Edetate Disodium, Polyquaternium-1 (0.001% preservative). Preservative-free (PF) product available for patients allergic or intolerant to benzalkonium chloride Systane Balance Eye Drops 10ml is a lubricating eye drop that helps replenish the tear films oil layer to provide temporary relief from burning and irritated eyes caused by dryness. preservative free (PF) eye drops for disinfection prior to intravitreal injections or implants when povidone-iodine cannot be used (unlicensed medicine) -Drug Safety Update (Mar 2019) Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects

Guidance on the responsibilities for Red Drugs can be found here. Red Drugs would usually by prescribed by the hospital for the duration of the course. Primary care prescriber initiation or continuation of treatment not recommended except by Specialist GP and community paediatric prescribing. All information is courtesy of the FDA. Prior eye drop recalls include EzriCare, Dr. Berne’s and LightEyez These medicines are considered suitable for GP prescribing following specialist initiation, including titration of dose and assessment of efficacy. Reserved for visualisation of the vitreous in a small number of procedures and for peri-ocular administration. NICE TA590: Fluocinolone acetonide intravitreal implant for treating recurrent non-infectious uveitis

reconstituted with 5mls of sodium chloride 0.9%; more than 0.1ml is drawn up into a syringe and the dose then adjusted to 0.1ml; it is recommended that the remaining solution is discarded United States National Nanotechnology Initiative. https://www.nano.gov/nanotech-101/special. Accessed April 5, 2018.Figure 1. Illustration depicting the increased surface area of nano-sized materials. Discontinue use and seek medical advice if you experience eye pain, changes in vision, or worsening redness or irritation. According to the recall, both products contain methylsulfonylmethane (MSM), an unapproved drug illegally marketed in the U.S., the federal health regulator reported.

Lane S, Paugh JR, Webb JR, Christensen MT. An evaluation of the in vivo retention time of a novel artificial tear as compared to a placebo control. Poster presented at: ARVO; May 3-7, 2009; Fort Lauderdale, Florida. MHRA: Drug Safety Update(Jan21): Aminoglycosides (gentamicin, amikacin, tobramycin, and neomycin): increased risk of deafness in patients with mitochondrial mutations For the management of glaucoma for patients already on the two constituent products separately to reduce eye drop burden and improve compliance Tell your doctor right away if you have any serious side effects, including: eye pain, change in vision, continued eye redness/irritation.There is no requirement for full Amber Drug Guidance. Generic Amber Level 1 Drug Guidance detailing responsibilities and information sources is available here Other forms of over-the-counter dry eye treatment, as reflected in our ranking, can include gels or ointments (often used at bedtime).