Synergetic ingredients: Works well with most ingredients but especially well with humectants like hyaluronic acid and occlusive ingredients that help trap the moisture in the skin.

Panethol’s main benefit is that it helps to draw water into the skin. Acting as a humectant, panthenol binds to water molecules and holds them in the skin. Hydrated skin is able to function properly and is responsible for dewy, plumped-looking skin. This makes panthenol great for skin types that endure harsh climates or air conditioning and heating as it is able to compensate for some of the transepidermal water loss that occurs in these environments. Transepidermal water loss refers to the loss of moisture that occurs from our skin to the environment. As we age our skin’s ability to minimize water loss reduces, resulting in dehydrated skin. Dehydrated skin is often responsible for that dullness and matte look.

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Similarly, panthenol may help to protect the new skin when healing. While this may be an added bonus for small cuts and marks for pimples it is not recommended for any open wound or large damaged area. Adamietz, I. A., Rahn, R., Bottcher, H. D., Schafer, V., Reimer, K., and Fleischer, W. [Prevention of radiochemotherapy-induced mucositis. Value of the prophylactic mouth rinsing with PVP-iodine solution]. Strahlenther.Onkol. 1998;174(3):149-155. View abstract.

Panthenol is a compound that's structurally similar to vitamin B5, or pantothenic acid. It's also known as provitamin B5 because it converts into vitamin B5 in the skin. Chemically, pantothenol is an alcohol, which means it has a hydroxyl group (an oxygen and a hydrogen bonded together). This hydroxyl group is what makes panthenol different from pantothenic acid. Budde, J., Tronnier, H., Rahlfs, V. W., and Frei-Kleiner, S. [Systemic therapy of diffuse effluvium and hair structure damage]. Hautarzt 1993;44(6):380-384. View abstract.

Riu, M., Flottes, L., Le, Den R., Lemouel, C., and Martin, J. C. [Clinical study of Thiopheol in oto-rhino-laryngology]. Rev.Laryngol.Otol.Rhinol.(Bord.) 1966;87(9):785-789. View abstract. Rahn R, Adamietz IA, Boettcher HD, et al. Povidone-iodine to prevent mucositis in patients during antineoplastic radiochemotherapy. Dermatology 1997;195(Suppl 2):57-61. View abstract. Ricci F, Masini F, Fossati B, et al. Combination therapy with hydrogen peroxide (4%), salicylic acid (0.5%) and D-panthenol (4%): efficacy and skyn tolerability in common acne vulgaris during sun exposure period. Eur Rev Med Pharmacol Sci. 2016;20(2):232-6. View abstract.