your doctor will check whether you have other risk factors that may increase the chance of a tear or detachment of one of the layers at the back of the eye (retinal detachment or tear, and retinal pigment epithelial detachment or tear), in which case Eylea must be given with caution. if you have a history of seeing flashes of light or floaters and if you have a sudden increase of size and number of floaters. Some of these may be serious and include blindness , a serious infection or inflammation inside the eye (endophthalmitis), detachment, tear or bleeding of the light-sensitive layer at the back of the eye (retinal detachment or tear), clouding of the lens (cataract), bleeding in the eye (vitreous haemorrhage), detachment of the gel-like substance inside the eye from the retina (vitreous detachment) and increase of pressure inside the eye , see section 2. Aflibercept, the active substance in Eylea, blocks the activity of a group of factors, known as Vascular Endothelial Growth Factor A (VEGF-A) and Placental Growth Factor (PlGF). In the clinical trials, there was an increased incidence of bleeding from small blood vessels in the outer layers of the eye (conjunctival haemorrhage) in patients with wet AMD receiving blood thinners.

Women of childbearing potential have to use effective contraception during treatment and for at least three further months after the last injection of Eylea.In patients with CRVO, a blockage occurs in the main blood vessel that transports blood away from the retina.

Unless you experience any problems or are advised differently by your doctor, there is no need for you to see your doctor between the injections. Allergic reactions like rash, itching (pruritus), hives (urticaria), and a few cases of severe allergy (anaphylactic/a­naphylactoid) reactions were reported.If any of the above applies to you, your doctor will consider this lack of information when treating you with Eylea. Eyelead, Optical Quality Products, αποτελεί μάρκα (brand) της ελληνικής εταιρίας VITORGAN με γυαλιά πρεσβυωπίας και ηλίου για παιδιά και ενήλικες. The following is a list of the side effects reported to be possibly related to the injection procedure or to the medicine. Push the filter needle into the centre of the vial stopper until the needle is completely inserted into the vial and the tip touches the bottom or bottom edge of the vial.

Read all of this leaflet carefully before you are given this medicine because it contains important information for you. Your doctor will monitor your response to treatment and may continue your treatment by gradually increasing the interval between your injections to maintain a stable condition.If you are pregnant or planning to become pregnant, discuss this with your doctor before treatment with Eylea. The systemic use of VEGF inhibitors, substances similar to those contained in Eylea, is potentially related to the risk of blood clots blocking blood vessels (arterial thromboembolic events) which may lead to heart attack or stroke. These serious side effects affecting the eyes occurred in less than 1 in 1,900 injections in clinical studies. Your doctor may decide to stop treatment with Eylea if it is determined that you are not benefiting from continued treatment. Patients with DME will be treated with one injection per month for the first five consecutive doses followed by one injection every two months thereafter.

Eylea has been shown to stop the growth of new abnormal blood vessels in the eye which often leak fluid or bleed. Your doctor will then decide whether the treatment interval between injections may be kept at every two months or be gradually extended in 2– or 4-weekly intervals if your condition has been stable. The other ingredients are: polysorbate 20 (E 432), sodium dihydrogen phosphate monohydrate (for pH adjustment), disodium hydrogen phosphate heptahydrate (for pH adjustment), sodium chloride, sucrose, water for injections. Eyelead είναι κοινοποιημένα στον ΕΟΦ, φέρουν Πιστοποίηση CE και κατέχουν βεβαίωση διακίνησης Ιατροτεχνολογικών Προϊόντων. VEGF levels are elevated in response causing the leakage of fluid into the retina and thereby causing macular oedema.if you are allergic to aflibercept or any of the other ingredients of this medicine (listed in section 6 ).